Endocrine Abstracts

IntroductionAdrenal abnormalities can be detected incidentally during the imaging performed for malignancies. These abnormalities may include adrenal pathological conditions independent of primary malignancies. Pheochromocytomas detected as part of some familial syndromes are often bilateral.In this report, we present a case of isolated sporadic bilateral pheochromocytoma that was incidentally detected during malignancy workup and staging, which is a rar...

IntroductionMEN 2A is an autosomal dominant disease, a familial syndrome with a mutation at RET proto-oncogene. %25 of medullary thyroid carcinoma (MTC) is a part of MEN 2A. Herein, we presented a patient with MEN 2A who was found to be heterozygos for RET mutation cause of the association of MTC and papillary thyroid carcinoma (PTC) is very rare.Case63 year old patient was admitted to the endocrinology clini...

IntroductionMucopolysaccharidosis type 4A (Morquio 4A) is an autosomal recessive lysosomal storage disease caused by a mutation in the gene encoding galactosamine 6 sulphatase (GALNS). It’s main clinical features include short stature, skeletal dysplasia, cloudy cornea, hearing loss and dental anomalies. Herein, a case of Morquio 4A, a rare cause of short stature is presented.Case reportA 41 year old fem...

IntroductionImmunological side effects related with use of immune checkpoint inhibitors (ICIs) are named as immune-related adverse events (irAEs). irAEs include clinical pictures such as autoimmune thyroiditis, hypophysitis, primary adrenal insufficiency and autoimmune diabetes mellitus. Nivolumab is an anti-PD-1 (anti-programmed cell death-1) monoclonal antibody approved for the treatment of malignant melanoma, advanced non-small cell lung cancer and ad...

Aims/IntroductionWe aimed to see whether Insulin Glargine U300 can provide better blood glucose control while reducing hypoglycemia in a more homogeneous population compared to previous studies.Materials and methodsFor evaluation of FBG, HbA1c and weight at 6 months and all variables final, observation windows of 120–240 days (4–8 months) and 240–480 days (9–16 months) after Insulin Glargi...

IntroductionTamoxifen is a selective estrogen receptor modulator used in the treatment of estrogen/progesterone receptor-positive breast cancer. Due to the increased frequency of breast cancer in the premenopausal period, the use of tamoxifen is quite common in patients with hormone receptor positivity. Although it is a commonly-used drug, the number of cases with elevated triglyceride levels is very few. Here, we present a case with severe hypertriglyce...

AimThe COVID-19 pandemic has affected the whole world, reducing hospital admissions of patients with chronic diseases. This study aims to evaluate the effects of difficulties experienced by diabetic patients in diabetes management on blood glucose regulation during the COVID-19 pandemic lockdown.MethodsThis study included 93 diabetic patients followed up in Endocrinology and Metabolic Diseases Clinic of Karad...

IntroductionHantaviruses are a group of viruses causing hemorrhagic fever with renal failure syndrome (HFRS). HFRS is a disease characterized by bleeding, thrombocytopenia, increased vascular permeability, and acute renal failure. Hypopituitarism associated with HFRS often results from necrosis in the pituitary gland caused by ischemia or infarction. HFRS may be difficult to diagnose due to its unclear clinical features. In this report, we present a pati...

IntroductionGraves’ Disease resistance to anti-thyroid treatment and poor treatment compliance with levothyroxine treatment (pseudomalabsorption) are not common conditions. We presented this case because of the inability to provide euthyroidism with anti-thyroid treatment before the surgery and with levothyroxine after the surgery in the same patient.Case ReportA 24-year-old female patient was admitted w...

Objective11-Beta Hydroxylase deficiency (11ß0HD) is a rare form of congenital adrenal hyperplasia, resulting in glucocorticoid deficiency, virilization and hypertension. In the literature, there are rare case reports of successful pregnancy in a patient with genetically confirmed classic 11ß0HD.CaseOur patient, now age 31, was diagnosed at birth with ambiguous genitalia. There was no family history ...